©The Author(s) 2025.
World J Clin Oncol. Dec 24, 2025; 16(12): 112626
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.112626
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.112626
Table 1 Clinicopathological parameters in gastric cancer patients, n (%)
| Parameter | YY1 | χ² | P value | |
| High expression | Low expression | |||
| Gender | ||||
| Male | 54 (77.1) | 22 (71) | 0.440 | 0.507 |
| Female | 16 (22.9) | 9 (29) | - | - |
| Age (years) | ||||
| < 61 | 12 (17.1) | 8 (25.8) | 1.015 | 0.314 |
| ≥ 61 | 58 (82.9) | 23 (74.2) | - | - |
| Tumor location | ||||
| Upper | 51 (72.9) | 24 (77.4) | 0.234 | 0.629 |
| Middle + lower | 19 (27.1) | 7 (22.6) | - | - |
| Tumor size (cm) | ||||
| < 6 cm | 45 (64.3) | 21 (67.7) | 0.113 | 0.736 |
| ≥ 6 cm | 25 (35.7) | 10 (32.3) | - | - |
| Tumor differentiation | ||||
| Well + moderate | 8 (11.4) | 11 (40.8) | 8.140 | 0.004 |
| Poor + undifferentiated | 62 (88.6) | 20 (59.2) | - | - |
| Lymph nodes metastasis | 58 (84.1) | 13 (41.9) | 17.231 | < 0.001 |
| pTNM stage | ||||
| I + II | 31 (44.3) | 24 (77.4) | 9.510 | 0.002 |
| III + IV | 39 (55.7) | 7 (22.6) | ||
- Citation: Chen JW, Ouyang JJ, Wang ZH, Ma DM, Zhang Z, Teng Q, Yu G, Li XY. Yin Yang 1 activates JAK-STAT3-mediated epithelial-mesenchymal transition in Helicobacter pylori-induced gastric cancer progression. World J Clin Oncol 2025; 16(12): 112626
- URL: https://www.wjgnet.com/2218-4333/full/v16/i12/112626.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i12.112626