Expanding the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A multicenter study on uncommon peritoneal malignancies

doi:10.5306/wjco.v16.i12.112443

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Dec 24, 2025; 16(12): 112443
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.112443

Table 3 Multivariable Cox regression by primary tumor site

Primary tumor site	HR	95%CI	P value
Breast cancer (reference)	1.00	-	-
Small bowel	25.21	3.53-180.14	< 0.005
Biliary tract	32.53	4.22-250.70	< 0.005
Pancreas	24.34	1.62-365.44	0.021
Uterus	6.71	1.72-26.11	0.006
Sarcoma	2.38	0.46-12.34	0.30
MPM	1.33	0.30-5.83	0.70
Miscellaneous	1.05	0.32-3.38	0.94

Miscellaneous includes: Ovarian carcinosarcoma; gastrointestinal stromal tumor (previously treated with TKI, resistant); 2 jejunal NET; desmoplastic small round cell tumor; malignant Pheochromocytoma. HR: Hazard ratio; 95%CI: 95% confidence interval; MPM: Malignant peritoneal mesothelioma.

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Citation: Framarini M, D'Acapito F, Lippolis PV, Di Giorgio A, Di Pietrantonio D, Sommariva A, Sammartino P. Expanding the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A multicenter study on uncommon peritoneal malignancies. World J Clin Oncol 2025; 16(12): 112443
URL: https://www.wjgnet.com/2218-4333/full/v16/i12/112443.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i12.112443

Framarini M, D'Acapito F, Lippolis PV, Di Giorgio A, Di Pietrantonio D, Sommariva A, Sammartino P. Expanding the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A multicenter study on uncommon peritoneal malignancies. World J Clin Oncol 2025; 16(12): 112443 [PMID: 41480175 DOI: 10.5306/wjco.v16.i12.112443]

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