Expression patterns and clinical implications of chaperonin subunit 3 mRNA and protein in laryngeal squamous cell carcinoma

doi:10.5306/wjco.v16.i12.112161

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Dec 24, 2025; 16(12): 112161
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.112161

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Figure 7 Clustered regularly interspaced short palindromic repeats screen is used to identify the function of chaperonin-containing TCP1 subunit 3 by knocking them out and observing the effect on laryngeal squamous cell carcinoma. Laryngeal squamous cell carcinoma cell lines show a highly negative effect score, indicating that chaperonin-containing TCP1 subunit 3 knocking out may induce strongly inhibitory effect on laryngeal squamous cell carcinoma.

Citation: Mo BY, Wen JY, Chen GQ, Ling JW, He H, Qin ZL, Tian FY, Li Q, Li B, Li JD, He RQ, Qin DY, Li ZY, Chen G, Mo CH, Chen C, Yin SH, Yang L. Expression patterns and clinical implications of chaperonin subunit 3 mRNA and protein in laryngeal squamous cell carcinoma. World J Clin Oncol 2025; 16(12): 112161
URL: https://www.wjgnet.com/2218-4333/full/v16/i12/112161.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i12.112161

Mo BY, Wen JY, Chen GQ, Ling JW, He H, Qin ZL, Tian FY, Li Q, Li B, Li JD, He RQ, Qin DY, Li ZY, Chen G, Mo CH, Chen C, Yin SH, Yang L. Expression patterns and clinical implications of chaperonin subunit 3 mRNA and protein in laryngeal squamous cell carcinoma. World J Clin Oncol 2025; 16(12): 112161 [PMID: 41480162 DOI: 10.5306/wjco.v16.i12.112161]

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