©The Author(s) 2025.
World J Clin Oncol. Dec 24, 2025; 16(12): 111701
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.111701
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.111701
Figure 2 Immunochemical analysis revealed two distinct tumour components: Squamous cell carcinoma and small cell carcinoma.
The squamous cell carcinoma component demonstrated positive staining for cluster of differentiation (CD) 5, CD117, cytokeratin and p40, with a Ki-67 proliferation index of 30%. The small cell carcinoma component showed positivity for CD117, cytokeratin, synaptophysin and chromogranin A, exhibiting a higher Ki-67 proliferation index of 60%. Scale bars are 60 μm. At 200 × magnification. SCC: Squamous cell carcinoma; SmCC: Small cell carcinoma; CD: Cluster of differentiation; TdT: Deoxynucleotidyl transferase; CK: Cytokeratin; Syn: Synaptophysin; CgA: Chromogranin A.
- Citation: Shan BW, Yu JH, Ren T. Intrathyroidal thymic carcinoma comprising squamous cell and small cell carcinoma components: A case report. World J Clin Oncol 2025; 16(12): 111701
- URL: https://www.wjgnet.com/2218-4333/full/v16/i12/111701.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i12.111701