Intrathyroidal thymic carcinoma comprising squamous cell and small cell carcinoma components: A case report

Figure 1 The histomorphology of the tumour reveals two distinct components: Squamous cell carcinoma and small cell carcinoma. In the squamous cell carcinoma region: At 100 × magnification, abundant stroma components are visible, with nest of tumour cells forming islands separated by the stroma; at 200 × magnification, the tumour cells exhibit slightly eosinophilic cytoplasm, pale vacuolated nuclei, and prominent nucleoli. In the small cell carcinoma region: At 100 × magnification, the tumour cells are arranged in sheets, with minimal surrounding stroma; at 200 × magnification, the tumour cells display scanty cytoplasm, poorly defined cell borders, finely granular and lightly stained chromatin, and inconspicuous nucleoli. Scale bar is 60 μm. SCC: Squamous cell carcinoma; SmCC: Small cell carcinoma.