Group-specific component and 25-hydroxylase gene polymorphisms in nasopharyngeal carcinoma: Associations with susceptibility and radiotherapy response

Table 1 Comparison of general characteristics of the subjects, n (%)

Characteristic	Case group (n = 360)	Control group (n = 550)	P value
Age (years) (mean ± SD)	52.6 ± 11.3	51.8 ± 10.9	0.312
Gender			0.726
Male	256 (71.1)	385 (70.0)
Female	104 (28.9)	165 (30.0)
Smoking history			0.583
Yes	168 (46.7)	246 (44.7)
No	192 (53.3)	304 (55.3)
Drinking history			0.671
Yes	132 (36.7)	210 (38.2)
No	228 (63.3)	340 (61.8)
25-hydroxyvitamin D (nmol/L) (mean ± SD)	46.8 ± 18.5	62.3 ± 20.7	< 0.001
Hypertension	72 (20.0)	116 (21.1)	0.698
Diabetes	36 (10.0)	61 (11.1)	0.612
Hemoglobin (g/L) (mean ± SD)	132.5 ± 15.7	134.2 ± 14.9	0.128
White blood cell count (× 109/L) (mean ± SD)	6.8 ± 2.1	6.6 ± 1.9	0.156
Platelet count (× 109/L) (mean ± SD)	235.6 ± 58.4	241.3 ± 55.7	0.142
Albumin (g/L) (mean ± SD)	42.3 ± 4.5	43.1 ± 4.2	0.008
Total cholesterol (mmol/L) (mean ± SD)	4.8 ± 1.0	4.9 ± 0.9	0.113
Pathological type
Squamous cell carcinoma	276 (76.7)
Undifferentiated carcinoma	72 (20.0)
Other	12 (3.3)
TNM stage
Stage I	24 (6.7)
Stage II	84 (23.3)
Stage III	168 (46.7)
Stage IV	84 (23.3)
T stage
T1	36 (10.0)
T2	108 (30.0)
T3	144 (40.0)
T4	72 (20.0)
N-stage
N0	48 (13.3)
N1	132 (36.7)
N2	132 (36.7)
N3	48 (13.3)
M-stage
M0	324 (90.0)
M1	36 (10.0)
Tumor volume (cm3) (mean ± SD)	28.5 ± 15.7

M-stage: Distant metastasis; N-stage: Regional lymph node involvement; T stage: Tumor size/extent.