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©The Author(s) 2025.
World J Clin Oncol. Dec 24, 2025; 16(12): 111175
Published online Dec 24, 2025. doi: 10.5306/wjco.v16.i12.111175
Figure 5
Figure 5 Mechanisms of sirtuin 3 regulation of mitophagy. AMPK: AMP-activated protein kinase; ATP: Adenosine triphosphate; BNIP3: BCL2-interacting protein 3; CAT: Catalase; LC-3: Light chain 3; mTOR: Mammalian target of rapamycin; OSCP: Oligomycin sensitivity conferral protein; PINK1: Phosphatase and tensin homolog-induced putative kinase 1; ROS: Reactive oxygen species; SIRT3: Sirtuin 3; SOD2: Superoxide dismutase 2; TCA: Tricarboxylic acid; PGC-1α: Peroxisome proliferator-activated receptor γ coactivator 1α.


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