Systematic pan-cancer analysis reveals the prognostic and immunological roles of ectonucleoside triphosphate diphosphohydrolase 6

Figure 8 Functional enrichment analysis. A: The ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6) interactome was generated with GeneMANIA; B: 76 putative ENTPD6-binding partners were retrieved from STRING; C: A Venn diagram highlights the genes shared by GeneMANIA, STRING, and Gene Expression Profiling Interactive Analysis; D: A pan-cancer heatmap illustrates the correlation between ENTPD6 and ENTPD5/glycogen phosphorylase B expression; E and F: Kyoto Encyclopedia of Genes and Genomes pathway and Gene Ontology enrichment analyses delineate the functional landscape of ENTPD6-associated genes. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. ENTPD5: Ectonucleoside triphosphate diphosphohydrolase 5; PYGB: Glycogen phosphorylase B; KEGG: Kyoto Encyclopedia of Genes; GO: Gene Ontology.