©The Author(s) 2025.
World J Clin Oncol. Nov 24, 2025; 16(11): 111627
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.111627
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.111627
Figure 4 The correlation between ectonucleoside triphosphate diphosphohydrolase 6 expression and genetic alterations, as well as genomic instability.
A: Pan-cancer analyses of genomic changes in ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6) expression were conducted, including analyses of mutations, amplifications, and deep deletions; B: Genetic alterations of ENTPD6, including missense, frameshift deletion, and splice site mutations; C: ENTPD6 expression in different copy number alteration categories; D: The correlation between copy number alteration and ENTPD6 expression. CAN: Copy number alteration; VUS: Variant of uncertain significance; ENTPD6: Ectonucleoside triphosphate diphosphohydrolase 6; RSEM: RNA-Seq by Expectation Maximization; GSTIC: Genomic Identification of Significant Targets in Cancer.
- Citation: Wang G, Liu T, Zhang JX, Li YR, Zhu WJ, Wang JL, Dong WW, Zhang YY, Li YM, Yang LX, He LX, He WT. Systematic pan-cancer analysis reveals the prognostic and immunological roles of ectonucleoside triphosphate diphosphohydrolase 6. World J Clin Oncol 2025; 16(11): 111627
- URL: https://www.wjgnet.com/2218-4333/full/v16/i11/111627.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i11.111627