Primary testicular diffuse large B-cell lymphoma with gonadal vein tumor thrombus: A case report and review of the literature

Table 2 Treatment response of lymphoma with tumor thrombus reported in the literature

Ref.	Primary tumor site	Tumor thrombus site	Pathology	Treatment	Prognosis
Wagner et al[17], 1993	Right kidney	Renal vein and IVC	DLBCL	Right radical nephrectomy followed by 6 courses of CHOP chemotherapy	Significant mass reduction after 1 year
Yoneyama et al[24], 1998	Hepatic tumor of the left and caudate lobes	Portal vein	DLBCL	Left hepatic trisegmentectomy, caudate lobectomy and portal tumour thrombectomy followed by 6 courses of combination chemotherapy including CHOP and VP-16	4.5 years without recurrence after surgery
Matsumoto et al[37], 2004	Mesentery nodal	Portal vein and superior mesenteric vein	DLBCL	An open surgical biopsy followed by 7 courses of CHOP	7.5 years without recurrence after diagnosis
Hiraga et al[38], 2006	Porta hepatis	Portal vein	DLBCL	Biopsy followed by 8 courses of THP-COP	6 years without recurrence after the initial diagnosis
Natsuizaka et al[28], 2009	Liver and left spermatic cord	Portal vein	DLBCL	Percutaneous liver biopsy and left testis and spermatic cord were surgically resected followed by 6 courses of R-CHOP	Complete response maintained for 16 months after chemotherapy
Samlowski et al[39], 2011	Right upper pole of kidney, right adrenal gland and liver	Renal vein and IVC	DLBCL	Biopsy followed by R-CHOP	Partial response after 3 courses of chemotherapy
Chen et al[25], 2013	Left solid renal mass, retroperitoneal extension and adenopathy	Renal vein, IVC	DLBCL	Biopsy followed by R-CHOP	Complete response maintained for 47 months

IVC: Inferior vena cava; DLBCL: Diffuse large B-cell lymphoma; CHOP: Cyclophosphamide, doxorubicin, vincristine, and prednisone; THP-COP: Cyclophosphamide, pirarubicin, vincristine, and prednisone; R-CHOP: Cyclophosphamide, doxorubicin, vincristine, prednisolone, and rituximab.