Role of the gut microbiome in the development and prognosis of pediatric leukemia

Figure 3 Impact of antibiotics, proton pump inhibitors, and Clostridium difficile colonization on gut microbial diversity in hospitalized children[23]. Heatmaps of α-diversity metrics comparing species richness (left) and Shannon index (right) across the entire cohort. Each point represents an individual patient; boxplots denote the median, interquartile range, and full range. IC: Immunocompromised. Citation: Mohandas S, Soma VL, Tran TDB, Sodergren E, Ambooken T, Goldman DL, Weinstock G, Herold BC. Differences in gut microbiome in hospitalized immunocompetent vs. immunocompromised children, including those with sickle cell disease. Front Pediatr 2020; 8: 583446. Copyright ©The Author(s) 2020. Published by Frontiers Media S.A (Supplementary material).