ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role

doi:10.5306/wjco.v16.i11.110202

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Nov 24, 2025; 16(11): 110202
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.110202

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Figure 3 Hallmarks of cancer associated with ADAM metallopeptidase with thrombospondin type 1 motif 8, kallikrein-related peptidases 10 and 5 proteases. Orange arrow indicates promotion, and the black line indicates inhibition. Both lines (orange and black) indicate the association between a hallmark of cancer and these proteases, depending on the cellular context. ADAMTS-8: ADAM metallopeptidase with thrombospondin type 1 motif 8; KLK: Kallikrein-related peptidases.

Citation: Palacios Serrato EG, Medina-Abreu KH, Oropeza-Martínez E, Jacinto-Alemán LF, Macías-Silva M, Tecalco-Cruz AC. ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role. World J Clin Oncol 2025; 16(11): 110202
URL: https://www.wjgnet.com/2218-4333/full/v16/i11/110202.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i11.110202

Palacios Serrato EG, Medina-Abreu KH, Oropeza-Martínez E, Jacinto-Alemán LF, Macías-Silva M, Tecalco-Cruz AC. ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role. World J Clin Oncol 2025; 16(11): 110202 [PMID: 41355923 DOI: 10.5306/wjco.v16.i11.110202]

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