©The Author(s) 2025.
World J Clin Oncol. Nov 24, 2025; 16(11): 110202
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.110202
Published online Nov 24, 2025. doi: 10.5306/wjco.v16.i11.110202
Table 3 ADAM metallopeptidase with thrombospondin type 1 motif 8, kallikrein-related peptidases 10 and 5 in some human cancers
| Cancer | Expression of ADAMTS-8 | Expression of KLK10 | Expression of KLK5 |
| Breast cancer | 1 | 1 | 1 |
| Prostate cancer | - | - | 2 |
| Testicular cancer | - | 2 | 2 |
| Vaginal cancer | - | - | 2 |
| Ovarian cancer | - | 2 | 3 |
| Gastric cancer | 2 | 1 | 3 |
| Brain cancer | 2 | - | - |
| Lung cancer | 2 | 2 | - |
| Colorectal cancer | 2 | 3 | - |
| Esophageal squamous cell carcinoma | 2 | - | - |
| Hepatocellular carcinoma | 2 | - | - |
| Esophageal cancer | - | 2 | - |
| Acute lymphoblastic leukemia | - | 2 | - |
| Skin cancer | - | 3 | 3 |
| Colon cancer | - | 3 | - |
| Pancreatic cancer | - | 3 | - |
| Oral squamous cell carcinoma | - | - | 1 |
| Urinary bladder carcinoma cells | - | - | 3 |
- Citation: Palacios Serrato EG, Medina-Abreu KH, Oropeza-Martínez E, Jacinto-Alemán LF, Macías-Silva M, Tecalco-Cruz AC. ADAMTS-8 and kallikrein-related peptidases 10 and 5 proteases also have a tumor suppression role. World J Clin Oncol 2025; 16(11): 110202
- URL: https://www.wjgnet.com/2218-4333/full/v16/i11/110202.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i11.110202