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Basic Study
©The Author(s) 2025.
World J Clin Oncol. Oct 24, 2025; 16(10): 111213
Published online Oct 24, 2025. doi: 10.5306/wjco.v16.i10.111213
Figure 5
Figure 5 Krüppel-like factor 5-related pathways and possible mechanisms in lung cancer. A-F: Biocarta analysis: A: WNT_pathway; B: MAPK_pathway; C: FAS_pathway; D: TGFB_pathway; E: AMI_pathway; F: Intrinsic_ pathway; G-L: GO analysis: G: Cytokines; H: Execution_phase_ of_apoptosis; I: Protein_acetylation; J: Regulation of RNA splicing; K: Bicellular tight junction assembly; L: MRNA splicing by splicing exosomes; M: A possible new mechanism is that abnormal transcription of Krüppel-like factor 5 promotes lung squamous-cell carcinoma progression by activating related signaling pathways (such as Wnt and so on). KLF5: Krüppel-like factor 5; Wnt3a: A member of the Wnt signaling pathway.


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