Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma

Figure 2 Krüppel-like factor-5 expression in the lung tissues or sera of patients. A-C: Krüppel-like factor-5 (KLF5) in lung squamous-cell carcinoma (LUSC): B: KLF5 in Adj-Ca tissues of LUSC; C: KLF5 ng/mg wet lung tissues (n = 60), ^bP < 0.01; D-F: KLF5 in lung adenocarcinoma (LUAD): E: KLF5 in Adj-Ca tissues of LUAD; F: KLF5 ng/mg wet lung tissues (n = 60); G: The positive rates of serum KLF5 (> 800 ng/mL) in LUSC, chronic pneumonia and normal control, ^fP < 0.01; H: Receiver operating characteristic curve of circulating KLF5 Levels for LUSC diagnosis. Adj-Ca: Adjacent cancerous tissues; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; KLF5: Krüppel-like factor 5; LUAD: Lung adenocarcinoma; LUSC: Lung squamous-cell carcinoma; MIF: Multiplex immunofluorescence; LC: Lung cancer; CP: Chronic pneumonia; NC: Normal control; ROC: Receiver operating characteristic.