Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma

Table 3 Univariate/multivariate analysis of strong Krüppel-like factor 5 expression in lung squamous-cell carcinoma

	Univariate			Multivariate
	HR	P > |z|	95%CI	HR	P > |z|	95%CI
KLF5 expression
Strong vs weak	3.050	0.002	1.741-5.326	3.122	0.003	1.725-5.458
Gender
Male vs female	1.704	0.052	0.994-2.921	1.121	0.706	0.622-2.015
Age (years)
≤ 60 vs > 60	1.115	0.628	0.717-1.733	1.365	0.826	0.845-2.209
Diameter (cm)
≤ 2 vs > 2	1.497	0.081	0.952-2.335	0.806	0.497	0.435-1.506
Differentiation
Well vs Mid/poor	3.216	< 0.001	0.886-3.021	2.012	< 0.001	0.065-2.688
LNM
No vs Mip/Mim	2.095	< 0.001	1.258-2987	2.095	< 0.001	1.197-3.667
Staging with TNM
I-II vs III/IV	0.925	0.642	0.432-1.586	1.515	0.082	0.948-2.422

HR: Hazard ratio; KLF5: Krüppel-like factor 5; LNM: Lymph node metastasis; Mid: Middle differentiation; Mim: Mediastinal metastasis; Mip: Ipsilateral peribronchial metastasis; No: No regional lymph node metastasis; TNM: Tumor node metastasis staging.