©The Author(s) 2025.
World J Clin Oncol. Oct 24, 2025; 16(10): 111213
Published online Oct 24, 2025. doi: 10.5306/wjco.v16.i10.111213
Published online Oct 24, 2025. doi: 10.5306/wjco.v16.i10.111213
Table 2 Clinicopathological characteristics of positive Krüppel-like factor 5 expression in lung squamous-cell carcinoma
| Groups | No. of patient (%) | KLF5 positive (n) | % | χ2 | P value |
| Lung cancer | 60 | 51 | 85.0 | - | - |
| Gender | |||||
| Male | 51 | 43 | 84.3 | 0.023 | 0.879 |
| Female | 9 | 8 | 88.9 | ||
| Age (years) | |||||
| ≤ 60 | 28 | 23 | 82.1 | 0.047 | 0.828 |
| > 60 | 32 | 28 | 87.5 | ||
| Tumor diameter (cm) | |||||
| ≤ 2 | 15 | 12 | 80.0 | 0.044 | 0.835 |
| > 2 | 45 | 39 | 86.7 | ||
| Differentiation | |||||
| Well | 18 | 11 | 61.1 | 8.989 | 0.003a |
| Moderate/poor | 42 | 40 | 95.2 | ||
| Lymph node metastasis | |||||
| Without | 16 | 10 | 62.5 | 6.424 | 0.011a |
| With | 44 | 41 | 93.2 | ||
| TNM staging | |||||
| I-II | 49 | 41 | 83.7 | 0.020 | 0.889 |
| III-IV | 11 | 10 | 90.9 | ||
| Five-year survival | |||||
| Yes | 19 | 17 | 89.5 | 0.074 | 0.786 |
| No | 41 | 34 | 82.9 |
- Citation: Shi Y, Sai WL, Chen JL, Qiu LW, Yao M, Zhao J, Yao DF. Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma. World J Clin Oncol 2025; 16(10): 111213
- URL: https://www.wjgnet.com/2218-4333/full/v16/i10/111213.htm
- DOI: https://dx.doi.org/10.5306/wjco.v16.i10.111213