Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma

doi:10.5306/wjco.v16.i10.111213

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Oct 24, 2025; 16(10): 111213
Published online Oct 24, 2025. doi: 10.5306/wjco.v16.i10.111213

Table 1 Summary of the intensity of KLF5 expression in lung tissues

Group	n	KLF5		χ²	P value	KLF5 intensity				Z value	P value
Group	n	Pos	Neg	χ²	P value	-	+	++	+++	Z value	P value
LUAD	60	39	21	2.749	0.097	21	29	9	1	5.059	0.168
Adj-Ca	60	29	31			31	19	10	0
LUSC	60	51	9	61.702	< 0.001	9	3	27	21	74.278	< 0.001
Adj-Ca	60	7	53			53	5	2	0

Adj-Ca: Adjacent cancerous tissues; KLF5: Krüppel-like factor 5; LUAD: Lung adenocarcinoma; LUSC: Lung squamous-cell carcinoma; Neg: Negative KLF5; Pos: Positive KLF5.

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Citation: Shi Y, Sai WL, Chen JL, Qiu LW, Yao M, Zhao J, Yao DF. Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma. World J Clin Oncol 2025; 16(10): 111213
URL: https://www.wjgnet.com/2218-4333/full/v16/i10/111213.htm
DOI: https://dx.doi.org/10.5306/wjco.v16.i10.111213

Shi Y, Sai WL, Chen JL, Qiu LW, Yao M, Zhao J, Yao DF. Abnormal expression and potential clinical value of oncogenic Krüppel-like factor-5 in lung squamous cell carcinoma. World J Clin Oncol 2025; 16(10): 111213 [PMID: 41178930 DOI: 10.5306/wjco.v16.i10.111213]

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