Neoadjuvant immunotherapy in resectable hepatocellular carcinoma: A meta-analysis of the current evidence

Figure 2 Forest plot. A: Major pathological response. Log(odds) forest plot for major pathological response following neoadjuvant immunotherapy in resectable hepatocellular carcinoma. Pooled odds ratio (OR) = 0.28 [95% confidence interval (95%CI): 0.19-0.41]; B: Overall response rate (ORR). Log(odds) forest plot for ORR following neoadjuvant immunotherapy. Pooled OR = 0.54 (95%CI: 0.25-1.14); C: Pathological complete response (pCR). Log(odds) forest plot for pCR in patients treated with neoadjuvant immunotherapy. Pooled OR = 0.26 (95%CI: 0.11-0.66); D: Resection rate. Log(odds) forest plot for resection rate after neoadjuvant immunotherapy. Pooled OR: 5.37 (95%CI: 2.70-10.66); E: Treatment-related adverse events (TRAEs). Log(odds) forest plot for grade 3-4 TRAEs. Pooled OR = 0.33 (95%CI: 0.22-0.50). OR: Odds ratio; 95%CI: 95% confidence interval.