Different types of tumor microvessels in stage I-IIIA squamous cell lung cancer and their clinical significance

Table 1 Baseline patient clinicopathological and treatment information

Clinical and pathological data	Patient groups				Significance level (P value)
	Main cohort (n = 180)		Training cohort (n = 62)
	n	%	n	%
Age (yr)
< 60	60	33.3	20	32.3	0.897
60-69	98	54.5	33	53.2
≥ 70	22	12.2	9	14.5
Tumor location
Central	119	66.1	38	61.3	0.493
Peripheral	61	33.9	24	38.7
Comorbidity
Absence	22	12.2	8	12.3	0.888
Presence	158	87.8	54	87.7
Histology
KSCC	56	31.1	21	33.9	0.687
NKSCC	124	68.9	41	66.1
Tumor grade
G1	57	31.7	23	37.1	0.325
G2	88	48.9	32	51.6
G3	35	19.4	7	11.3
T stage
T1a	9	5.0	8	12.9	0.039a
T1b	15	8.3	6	9.7
T2a	82	45.6	34	54.8
T2b	17	9.4	5	8.1
T3	57	31.7	9	14.5
N stage
N0	48	26.7	22	35.5	0.411
N1	88	48.9	26	41.9
N2	44	24.4	14	22.6
Stage
I	30	16.7	20	32.3	0.03a
II	73	40.6	22	32.4
III	77	42.8	20	32.3
Type of surgery
Lobectomy	84	46.7	40	64.4	0.001a
Bilobectomy	6	3.3	5	8.1
Pneumonectomy	86	47.8	13	21.0
Segmentectomy	4	2.2	4	6.5
Adjuvant therapy
Absent	51	28.3	27	43.5	0.002a
Chemotherapy	68	37.8	10	16.1
Radiation therapy	38	21.1	21	33.9
Chemo- and radiotherapy	23	12.8	4	6.5

^aP < 0.05, the differences between groups are statistically significant.

KSCC: Keratinizing squamous cell carcinoma; NKSCC: Nonkeratinizing squamous cell carcinoma.