Deregulation of interferon-gamma receptor 1 expression and its implications for lung adenocarcinoma progression

Figure 2 IFNGR1 and JAK1/2 are downregulated in lung adenocarcinoma. IFNGR1, IFNAR1, JAK1, and JAK2 expression in human lung adenocarcinoma (LUAD) tumors compared to normal tissue tumors. A-D: Selamat Lung dataset; E: The Cancer Genome Atlas from the University of ALabama at Birmingham CANcer data analysis Portal. Expression of IFNGR1 in LUAD based on the patient´s smoking habits. Reformed smoker 1 (< 5 years); Reformed smoker 2 (> 15 years). Results are considered significant (P < 0.05) in all cases, with the exception of IFNAR1 (NS: Not significant).