Guidelines
Copyright ©The Author(s) 2022.
World J Clin Oncol. Apr 24, 2022; 13(4): 237-266
Published online Apr 24, 2022. doi: 10.5306/wjco.v13.i4.237
Table 8 Dose constraints for moderate hypofractionation
Organ
Concurrent RT/ChT (55 Gy/20 fx)
Sequential RT/ChT (55 Gy/20 fx)
RT (50-58 Gy/15 fx)
RT (50-60 Gy/15 fx)[138]
Spinal cordMD 44 Gy (0.1 cc)Dmax ≤ 36MD 42 Gy (0.1 cc)MD < 38 Gy
Esophagus1MD < 55 Gy (1 cc)V42 < 32%MD < 52 Gy (1 cc)MD < 50 Gy (1 cc), V45 < 10 cc
Lungs-GTVV20 < 35%, MD < 18 GyV20 < 25%-30%, MD ≤ 15 GyV19 < 35%, MD < 16 GyV20 < 30%, V5 < 60%, MD < 20 Gy
HeartV30 < 36%V33 < 25%D100% < 33 Gy, D67% < 40 Gy, D33% < 52 GyMD 63 Gy, V57 < 10 cc
Great vesselsNANAMD 58 GyMD 63 Gy, V57 < 10 cc
Trachea, carina and main bronchusNANAMD 58 GyMD 63 Gy, V57 < 10cc
RibMD < 63 GyNAV30 < 30 ccMD 63 Gy; V30 < 30cc