Immunotherapy: A new standard in the treatment of metastatic clear cell renal cell carcinoma

Table 1 Poor prognostic factor

Poor prognostic factor	MSKCC	IMDC
Time from diagnosis to treatment	< 12 mo	< 12 mo
Hemoglobin	< lower limit of normal	< lower limit of normal
Corrected serum calcium	> 10 mg/dl (2.5 mmol/L)	> upper limit of normal
Karnofsky performance score	< 80%	< 80%
Neutrophil count	/	> upper limit of normal
Platelet count	/	> upper limit of normal
Lactate dehydrogenase	> 1.5 x upper limit of normal	/
Good risk	0 risk factor	0 risk factor
Intermediate risk	1 or 2 risk factors	1 or 2 risk factors
Poor risk	3, 4 or 5 risk factors	3, 4, 5 or 6 risk factors

MSKCC: Memorial Sloan Kettering Cancer Center; IMDC: International mRCC Database Consortium.