Role of mammogram and ultrasound imaging in predicting breast cancer subtypes in screening and symptomatic patients

Table 5 Binomial univariate and multivariate logistic regressions (HER2+ vs Non HER2+)

HER2+ vs Non HER2+		Univariate			Multivariate (AUC = 0.747)
		P	OR	CI	P	OR	CI
Margins1	Microlobulated	c	3.92	(1.830 9.410)	b	3.26	(1.469 8.026)
	Circumscribed	Not significant			Not significant
High-risk microcalcifications	Present	c	3.51	(1.804 6.821)	c	3.38	(1.685 6.816)
Adler’s Index	High	a	2.32	(1.203 4.437)	a	1.99	(0.999 4.010)

¹Spiculated ultrasound margins were set as the baseline with OR = 1.

^aSignificant at the 0.001 level.

^bSignificant at the 0.01 level.

^cSignificant at the 0.05 level.

^dSignificant at the 0.10 level.

Area under the receiver operating characteristic curve for multivariate regression on ultrasound (US) margins, MM high-risk microcalcifications, and US Adler index (low or intermediate/high). AUC: Area under the receiver operating characteristic curve.