Diacerein treatment prevents colitis-associated cancer in mice

Figure 3 Diacerein prevents inflammation-induced colon carcinogenesis. Swiss mice underwent colon cancer induction by azoxymethane and dextran sulphate sodium treatment over 3 mo, control. A: Tumor number (n = 29–36 mice/group); B: Tumor size (n = 25–33 mice/group); C: Analysis of pro-inflammatory protein expression (p-IKK, p-JNK) by immunoblot (Supplementary Figure 2). Data are presented as mean ± standard error. ^aP < 0.05; ^cP < 0.001.