Is there a role for treatment-oriented surgery in liver metastases from gastric cancer?

Table 2 Results of the review

Ref.	OS1 (%)	OS2 (%)	OS3 (%)	OS5 (%)	Systemic recurrence (%)	Hepatic recurrence (%)	Survival (mo)	DFS (months)	Long survivor (pt. alive > 5 yr)	Median follow-up (mo)
Ambiru et al[10]	71.1	27	-	18	77.5	94	12	-	6	88
Imamura et al[23]	47	22	22	0	-	-	-	-	0	22.7
Fujii et al[41]	60	20	20	10	80	-	16.3	8.2	1	-
Okano et al[11]	77	-	34	34	74	85	21	8.2	3	36
Zacherl et al[15]	35.7	28.6	14.3	0	86.7	-	8,8	-	0	-
Saiura et al[5]	50	-	30	20	-	-	25	-	2	-
Sakamoto et al[46]	76.2	38.3	38.3	38.3	68	86.6	21.4	-	5	17
Shirabe et al[33]	64	43	26.1	26.1	83.3	73.3	-	-	4 (2S/2M)	-
Roh et al[80]	72.7	-	-	27.3	91	72.7	19 (13S/74.3M)	-	2	-
Koga et al[24]	76	-	48	42	67	75	34	-	8	16
Sakamoto et al[39]	-	-	-	11	81	62	31	-	2 (1S/1M)	-
Cheon et al[47]	75.3	38.4	31.7	20.8	63.6	78.6	17.9	-	3	15.5
Morise et al[25]	56.3	36.5	27.3	27.3	55.5	-	13	-	3	117
Thelen et al[59]	80	60	-	60	-	-	-	-	5S	-
Ueda et al[34]	38 (DFS 33)	-	16 (DFS 10)	10 (DFS 10)	79.1	15.7	9	-	2	8.9
Tiberio et al[26]	33	10	6	4	-	-	7	-	-	19
Nomura et al[56]	-	-	-	30.8	75	58.3	21	-	4	-
Makino et al[27]	81.3	-	46.4	37.1	56.3	25	31.2	-	4 (2S/2M)	16
Tsujimoto et al[35]	-	-	-	-	76.4	23.5	34 (19S/38M)	-	5 (2S/3M)	29.3
Garancini et al[12]	68 (DFS 51)	-	31 (DFS 25)	19 (DFS 14)	66.6	61.9	11	-	3	20
Miki et al[29]	73.9	-	42.8	36.7	72	83.3	33.4	-	9	-
Takemura et al[8]	84 act (DFS act 42)	-	50 act (DFS act 27)	37 act (DFS act 27)	67	56.2	34	9	23	27
Schildberg et al[13]	-	-	-	13 (29M/0S)	-	-	21 (single) 4 (multiple)	-	4M	-
Wang et al[77]	43.3	30	16.7	16.7	-	83.3	-	11	-	5 (1S/4M)
Yang et al[78]	38.5	30.8	-	-	-	-	-	12	-	-
Aoyagi et al[57]	76.5	52.9	35.3	17.6	-	-	-	29	-	3
Qiu et al[4]	96 (DFS 56)	-	70.4 (DFS 22.3)	29.4 (DFS 11.1)	-	96	16	38	18	5S
Viganò et al[37]	-	-	-	-	-	65	61.5	52.3	13	3 (2S/1M)
Aizawa et al[44]	-	-	-	-	-	-	-	13	-	12S
Komeda et al[51]	78.3	-	40.1	40.1	-	66.7	56.2	22.3	-	4
Wang et al[48]	56.4 (DFS 30.8)	25.6 (DFS 12,8)	17.9 (DFS 10.3)	10.3 (DFS 7.7)	-	65.7	43.4	14	8	4
Kinoshita et al[14]	77.3 (DFS 43.6)	-	41.9 (DFS 32.4)	31.1 (DFS 30.1)	-	75	72.4	31.1	9.4	80
Ohkura et al[49]	88.9	-	29.6	-	-	69.2	77.7	-	-	-
Shinohara et al[58]	86 (DFS 42)	-	26 (DFS 26)	26 (DFS 26)	-	-	-	22 (R0 27)	-	-
Tiberio et al[30]	50.4	21.0	14.0	9.3	-	92.6	36.7	13	-	3S
Guner et al[54]	79.1	-	40.6	30	-	61,2	63.4	24	-	-
Oguro et al[43]	71.3	-	41.8	13.9	-	69,2	30.7	20.1	15.2	-
Tatsubayashi et al[42]	-	-	-	32 (59 M)	-	61	15	49	-	-
Li et al[81]	73.5	55.7	36.9	24.5	-	-	-	26.15	-	-
Li et al[38]	80.5	-	41.5	24.4	-	-	-	43	-	-
Markar et al[17]	-	-	42	31	-	-	-	-	-	-
Song et al[28]	87.5	-	47.6	21.7	-	80.2	58.4	34	-	-
Li et al[79]	MIS 90.1 open 90.1	-	27.3 42.4	9.1 24.2	-	-	-	30.7 48.5	-	-
Ministrini et al[31]	49.9	-	19.4	11.6	-	-	61	12	-	-
Nishi et al[45]	88.9	-	17.8	-	-	80	-	21.5	4.7	-
Nonaka et al[40]	78.0	-	33.3	22.2	-	-	-	30	9.5	-
Sano et al[53]	-	-	-	32	25	-	-	30	9	-

-: Missing or not clearly reported in the article; OS: Overall survival; DFS: Disease-free survival; S: Synchronous; M: Metachronous; MIS: Mini-invasive surgery; ACT: Actuarial survival.