Assessment of breast cancer immunohistochemistry and tumor characteristics in Nigeria

Table 2 Association of estrogen receptor and progesterone receptor with prognostic markers (n = 259)

Age	Hormonal receptors						Total	P value
	ER + ve	ER - ve	PR + ve	PR - ve	HER/2 neu + ve	HER/2 neu - ve
< 50	73 (50.70%)	17 (11.80%)	34 (23.60%)	9 (6.30%)	8 (5.60%)	3 (2.10%)	144	0.01
≥ 50	40 (34.80%)	35 (30.40%)	8 (7.00%)	3 (2.60%)	15 (13.00%)	14 (12.20%)	115
Grading
I	35 (56.50%)	18 (29.00%)	3 (4.80%)	2 (3.20%)	3 (4.80%)	1 (1.60%)	62	0.02
II	55 (42.00%)	23 (17.60%)	29 (22.10%)	5 (3.80%)	13 (9.90%)	6 (4.60%)	131
III	23 (34.80%)	11 (16.70%)	10 (15.20%)	5 (7.60%)	7 (10.60%)	10 (15.20%)	66
Tumour size
< 2.0 cm	35 (56.50%)	18 (29.00%)	3 (4.80%)	2 (3.20%)	3 (4.80%)	1 (1.60%)	62	0.02
2-5 cm	55 (42.00%)	23 (17.60%)	29 (22.10%)	5 (3.80%)	13 (9.90%)	6 (4.60%)	131
> 5.0 cm	23 (34.80%)	11 (16.70%)	10 (15.20%)	5 (7.60%)	7 (10.60%)	10 (15.20%)	66
Lymph node involvement
No	11 (50.00%)	3 (13.60%)	3 (13.60%)	2 (9.10%)	2 (9.10%)	1 (4.50%)	22	0.03
1-3	86 (43.90%)	43 (21.90%)	34 (17.30%)	6 (3.10%)	19 (9.70%)	8 (4.10%)	196
≥ 4	16 (39.00%)	6 (14.60%)	5 (12.20%)	4 (9.80%)	2 (4.90%)	8 (19.50%)	41

ER: Estrogen receptor; PR: Progesterone receptor; HER/2 neu: Human epidermal growth factor receptor-2.