Copyright
©The Author(s) 2019.
World J Clin Oncol. Mar 24, 2019; 10(3): 149-160
Published online Mar 24, 2019. doi: 10.5306/wjco.v10.i3.149
Published online Mar 24, 2019. doi: 10.5306/wjco.v10.i3.149
Figure 2 Immunohistochemistry analysis.
Immunohistochemistry analysis of the control mouse xenograft, tumor xenograft treated with 3 mg/kg RO7070179, which exhibited 53% decrease in hypoxia-inducible factor 1α (HIF-1α) mRNA, and the tumor xenograft treated with 10 mg/kg RO7070719, which exhibited 76% decrease in HIF-1α mRNA. HIF-1α: Hypoxia-inducible factor 1α; VEGF: Vascular epidermal growth factor.
- Citation: Wu J, Contratto M, Shanbhogue KP, Manji GA, O’Neil BH, Noonan A, Tudor R, Lee R. Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellular carcinoma. World J Clin Oncol 2019; 10(3): 149-160
- URL: https://www.wjgnet.com/2218-4333/full/v10/i3/149.htm
- DOI: https://dx.doi.org/10.5306/wjco.v10.i3.149