Procathepsin D and cancer: From molecular biology to clinical applications

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Nov 10, 2010 (publication date) through Apr 17, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Nov 10, 2010; 1(1): 35-40
Published online Nov 10, 2010. doi: 10.5306/wjco.v1.i1.35

Table 1 Cellular localization of procathepsin D/cathepsin D

Form	Localization	Process
Pre-procathepsin	Rough endoplasmic reticulum	Synthesis
Procathepsin	Golgi apparatus	Modification of oligosaccharides
Procathepsin	Prelysosomal compartments	Cleavage of the activation peptide
Single chain cathepsin	Lysosomes	Proteolytic processing, triming of oligosaccharides
Mature cathepsin	Lysosomes

Citation: Vetvicka V, Vashishta A, Saraswat-Ohri S, Vetvickova J. Procathepsin D and cancer: From molecular biology to clinical applications. World J Clin Oncol 2010; 1(1): 35-40
URL: https://www.wjgnet.com/2218-4333/full/v1/i1/35.htm
DOI: https://dx.doi.org/10.5306/wjco.v1.i1.35