Arctic ground squirrel neuronal progenitor cells resist oxygen and glucose deprivation-induced death

Figure 1 Cultures of human neuronal progenitor cells express TUJ1 and MAP2ab at 14 d in vitro (left) and die within 24 h of re-oxygenation (right). Cultures were deprived of oxygen and/or glucose for 48 h and resources were replaced for 24 h before assaying for viability (A), proportion NPC to total cells (B) or cell death (C). Horizontal lines indicate P < 0.05; ANOVA followed by a Holm-Sidak test (A, B) or Kruskal-Wallis ANOVA on ranks followed by Dunn’s multiple comparisons (C). Mean ± SD. Only differences relative to control are shown. NPC: Neuronal progenitor cell.