Methionine sulfoxide reductase A: Structure, function and role in ocular pathology

doi:10.4331/wjbc.v2.i8.184

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Aug 26, 2011 (publication date) through Apr 25, 2024

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Aug 26, 2011; 2(8): 184-192
Published online Aug 26, 2011. doi: 10.4331/wjbc.v2.i8.184

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Figure 1 Scheme depicting the role of methionine sulfoxide reductase A and α-crystallin in methionine metabolism. Note the reversible nature of oxidation-reduction of methionine and its influence on the chaperone properties of α-crystallin. The inhibition of the apoptotic events from oxidative stress by αB crystallin is also presented in the figure. ROS: Reactive oxygen species.

Citation: Sreekumar PG, Hinton DR, Kannan R. Methionine sulfoxide reductase A: Structure, function and role in ocular pathology. World J Biol Chem 2011; 2(8): 184-192
URL: https://www.wjgnet.com/1949-8454/full/v2/i8/184.htm
DOI: https://dx.doi.org/10.4331/wjbc.v2.i8.184