Topic Highlight
Copyright ©2011 Baishideng Publishing Group Co.
World J Biol Chem. Jun 26, 2011; 2(6): 140-145
Published online Jun 26, 2011. doi: 10.4331/wjbc.v2.i6.140
Figure 1
Figure 1 The association of Ikaros proteins with Ikaros isoforms and Ikaros family members controls the activity of the Ikaros protein complex. The four main types of Ikaros family-containing protein complexes are shown. A: Homodimers of the most abundant Ikaros isoform (IK-1); B: Heterodimers of IK-1 with DNA-binding Ikaros isoforms; C: Heterodimers of IK-1 and DNA-nonbinding (DN) Ikaros isoforms - this complex does not bind DNA; D: Heterodimers of Ikaros with its other family members (e.g. Helios or Aiolos).