©The Author(s) 2025.
World J Biol Chem. Dec 5, 2025; 16(4): 111258
Published online Dec 5, 2025. doi: 10.4331/wjbc.v16.i4.111258
Published online Dec 5, 2025. doi: 10.4331/wjbc.v16.i4.111258
Figure 1 Odd-chain β-oxidation of pentadecanoic acid culminates in propionyl-CoA, which is carboxylated to succinyl-CoA and con verted to succinate, thereby replenishing the tricarboxylic-acid cycle.
Even-chain palmitate yields only acetyl-CoA and supplies no succinate; net stoichiometric difference is +1 succinate per mole pentadecanoic acid oxidized. C15:0: Pentadecanoic acid; C16:0: Palmitic acid; FAD: Flavin adenine dinucleotide; FADH2: Dihydroflavine-adenine dinucleotide; NAD: Nicotinamide adenine dinucleotide; NADH: Nicotinamide adenine dinucleotide; TCA: Tricarboxylic acid.
- Citation: Mercola J. Molecular and cellular mechanisms of pentadecanoic acid. World J Biol Chem 2025; 16(4): 111258
- URL: https://www.wjgnet.com/1949-8454/full/v16/i4/111258.htm
- DOI: https://dx.doi.org/10.4331/wjbc.v16.i4.111258