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Case Control Study
©The Author(s) 2025.
World J Biol Chem. Dec 5, 2025; 16(4): 111104
Published online Dec 5, 2025. doi: 10.4331/wjbc.v16.i4.111104
Table 2 Genotypic and allelic frequencies of CD36 (rs1761667) (G/A) and (rs75326924) (C/T) polymorphisms in healthy pregnant controls (n = 200) and gestational diabetes mellitus cases (n = 200)
Genotype frequency
Genotype
Control, n = 200 (%)
Case, n = 200 (%)
P value
Odd ratio 95%CI
CD36 (rs1761667)
GG96 (44)64 (32)-1.0 (Refence)
GA58 (29)102 (51)0.00012.638 (1.695-4.190)
AA46 (23)34 (17)0.71031.109 (0.6386-1.895)
Allelic frequency
G250 (62.5)230 (57.5)0.14891.232 (0.9297-1.635)
A150 (37.5)170 (42.5)
Carriage rate
G+154 (77)166 (83)0.13360.6857 (0.4182-1.133)
G-46 (23)34 (17)
A+104 (52)136 (68)0.00110.5098 (0.3428-0.7628)
A-96 (48064 (32)
CD36 (rs75326924)
CC114 (57)82 (41)-1.0 (Refence)
CT55 (27.5)80 (40)0.00252.022 (1.279-3.164)
TT31 (15.5)38 (19)0.6781.704 (0.980-2.918)
Allelic frequency
C283 (70.75)244 (61)0.00461.546 (1.156-2.081)
T117 (29.25)156 (39)
Carriage rate
C+169 (84.5)162 (81)0.42731.279 (0.754-2.129)
C-31 (15.5)38 (19)
T+86 (43)118 (59)0.00190.524 (0.352-0.786)
T-114 (57)82 (41)


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