CD36 fatty-acid-transporter gene variants-CD36 G/A (rs1761667) and CD36 C/T (rs75326924) as biomarkers for risk-prediction in gestational diabetes mellitus

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World Journal of Biological Chemistry

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1949-8454

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Case Control Study

World J Biol Chem. Dec 5, 2025; 16(4): 111104
Published online Dec 5, 2025. doi: 10.4331/wjbc.v16.i4.111104

Table 1 Details of anthropometric parameters of controls and gestational diabetes mellitus cases, n (%)

Parameters	Controls (n = 200)	GDM (n = 200)	P value
Anthropometric parameters (mean ± SD)
Age (years)	26.74 ± 5.3	29.39 ± 5.7	0.0003^a
Gestational age	24.74 ± 3.9	25.65 ± 2.5	0.0077^a
Family history of diabetes
Yes	41 (19.3)	88 (43.3)	0.0001^a
No	159 (80.7)	112 (56.7)	0.0001^a
Body mass index (kg/m²)	23.97 ± 2.67	25.98 ± 2.38	0.0001^a
Systolic blood pressure	124.3 ± 7.73	126.8 ± 9.98	0.0066^a
Diastolic blood pressure	79.08 ± 6.44	81.39 ± 8.28	0.0020^a
Biochemical parameters (mean ± SD) (mg/dL)
Fasting plasma glucose	84.2 ± 4.2	99.9 ± 4.5	0.0001^a
Post prandial glucose	125.7 ± 24.57	159.9 ± 36.11	0.0001^a
Total cholesterol	176.7 ± 14.3	182.2 ± 22.2	< 0.091
Triglycerides	154.7 ± 20.36	181.5 ± 30.47	0.0001^a
High-density lipoprotein	51.7 ± 7.5	50.3 ± 6.9	0.0835
Low-density lipoprotein	69.53 ± 16.19	76.49 ± 22.96	0.0027^a
Serum creatinine	0. 09 ± 0.7	1.1 ± 0.5	0.0828

^aP < 0.05 showed association with gestational diabetes mellitus.

Data are represented as mean ± SD. GDM: Gestational diabetes mellitus.

Citation: Shamsad A, Gautam T, Singh R, Banerjee M. CD36 fatty-acid-transporter gene variants-CD36 G/A (rs1761667) and CD36 C/T (rs75326924) as biomarkers for risk-prediction in gestational diabetes mellitus. World J Biol Chem 2025; 16(4): 111104
URL: https://www.wjgnet.com/1949-8454/full/v16/i4/111104.htm
DOI: https://dx.doi.org/10.4331/wjbc.v16.i4.111104

Shamsad A, Gautam T, Singh R, Banerjee M. CD36 fatty-acid-transporter gene variants-CD36 G/A (rs1761667) and CD36 C/T (rs75326924) as biomarkers for risk-prediction in gestational diabetes mellitus. World J Biol Chem 2025; 16(4): 111104 [PMID: 41378247 DOI: 10.4331/wjbc.v16.i4.111104]

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