©The Author(s) 2025.
World J Biol Chem. Dec 5, 2025; 16(4): 109509
Published online Dec 5, 2025. doi: 10.4331/wjbc.v16.i4.109509
Published online Dec 5, 2025. doi: 10.4331/wjbc.v16.i4.109509
Figure 1 Regulatory mechanisms of pancreatic macrophage modulation in obesity pathogenesis.
The figure illustrates the pathological mecha nisms by which pancreatic macrophages, upon stimulation, undergo various pathological responses that ultimately lead to pancreatic fibrosis. TGF-β: Transforming growth factor beta; TNF-α: Tumor necrosis factor alpha; NF-κB: Nuclear factor-kappaB.
- Citation: Chen KR, Chen ZY, Liu FY, Xie CY, Hu J, Wang SY, Xu B, Xu TC. Macrophage-mediated metabolic dysregulation in the pancreas: Insights from obesity. World J Biol Chem 2025; 16(4): 109509
- URL: https://www.wjgnet.com/1949-8454/full/v16/i4/109509.htm
- DOI: https://dx.doi.org/10.4331/wjbc.v16.i4.109509