Mesenchymal stromal cell delivery as a potential therapeutic strategy against COVID-19: Promising evidence from in vitro results

Figure 1 Evaluation of characteristics of Wharton’s Jelly and bone marrow-mesenchymal stromal cells. A: Morphological characteristics of mesenchymal stromal cells (MSCs) derived from Wharton’s Jelly (WJ) tissue and bone marrow (BM). MSCs from both sources were characterized as spindle-shaped cells with a few internal vacuoles. Both WJ and BM-MSCs were successfully differentiated to “osteocytes”, “adipocytes”, and “chondrocytes”. White squares and black squares indicate the presence of calcium deposits and oil droplets, respectively. Black and orange arrows indicate the differentiated and undifferentiated state, respectively. a and e: Original magnification 20 ×, scale bars = 50 μm; b-d and f-h: Original magnification 10 ×, scale bars = 100 μm; B: Unlabeled WJ and BM-MSCs; C: Evaluation of CD marker expression by WJ and BM-MSCs. BM: Bone marrow; MSCs: Mesenchymal stromal cells; WJ: Wharton’s Jelly.