LIN28A: A multifunctional versatile molecule with future therapeutic potential

doi:10.4331/wjbc.v13.i2.35

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Mar 27, 2022 (publication date) through Apr 18, 2024

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Mar 27, 2022; 13(2): 35-46
Published online Mar 27, 2022. doi: 10.4331/wjbc.v13.i2.35

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Figure 2 Molecular pathways of LIN28A/let-7 axis. LIN28A binds to pri-let-7 in the nucleus to prevent its processing by Drosha and to pre-let-7 in the cytoplasm to prevent Dicer processing as well as facilitate its degradation.

Citation: Wu K, Ahmad T, Eri R. LIN28A: A multifunctional versatile molecule with future therapeutic potential . World J Biol Chem 2022; 13(2): 35-46
URL: https://www.wjgnet.com/1949-8454/full/v13/i2/35.htm
DOI: https://dx.doi.org/10.4331/wjbc.v13.i2.35