Restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis: A narrative review

Table 2 Studies comparing the intra-operative, short-term, and functional outcomes of open vs laparoscopic restorative proctocolectomy with ileal pouch-anal anastomosis

Ref.	Type of study	Number of patients	Operative time (min)	Blood loss (mL)	Mortality (%)	Hospital stay (d)	Post-operative complications (%)	Functional outcomes
Fajardo et al[10]	Retrospective	Open: 69 LS: 55	Open: 187 ± 52 LS: 266 ± 55e	Open: 284 ± 146 LS: 294 ± 274	Open: 0 LS: 0	Open: 7.8 ± 4.9 LS: 8.4 ± 6.0	Open: 59.4 LS: 50.1	Open: 5.1 ± 2.8 LS: 4.9 ± 4.92
Fleming et al[11]	Retrospective	Open: 339 LS: 337	Patients with an operative time > 336 min Open: 13.7%e LS: 36.6%e	Patients with transfusion Open: 8%a LS: 3.9a	Open: 0.6 LS: 0.5	Open: 7.9 ± 4.8 LS: 7.3 ± 4.3	Major Open: 29.74 LS: 16.84 Minor Open: 18.43 LS: 10.63	Not reported
Causey et al[12]	Retrospective	Open: 148 LS: 299	Not reported	Not reported	Open: 0 LS: 0	Not reported	Open: 18.2b LS: 29.8b	Not reported
Schiessling et al[13]	PRT1	Open: 21 LS: 21	Open: 200 ± 53 LS: 313 ± 52e	Open: 228 ± 119 LS: 261 ± 195	Open: 0 LS: 0	Open: 19.6 ± 20.5 LS: 12.3 ± 5.8	Open: 5 LS: 9.5	Open: 3. 5 ± 2.5 LS: 3.4 ± 2.52
Tajti et al[15]	Retrospective	Open: 22 LS: 23	Open: 185 ± 171c LS: 245 ± 511c	Units of blood transfusion Open: 3 ± 1.9 LS: 2 ± 1.7	Open: Not reported LS: Not reported	Open: 11.6 ± 3.4 LS: 11.5 ± 3.8	Sepsis Open: 27d LS: 0d	Open: 7.83 ± 3.285 LS: 7.81 ± 3.315
Benlice et al[14]	Retrospective	Open: 238 LS: 119	Higher in LS		Not evaluated		Similar incidence of incisional hernia and small bowel obstruction

¹Included patients with ulcerative colitis and familial adenomatous polyposis;

²Days to first ingestion;

³Based on a multivariate analysis: OR = 0.44 (0.27-0.70) (P = 0.01);

⁴Based on a multivariate analysis: OR = 0.67 (0.45–0.99) (P = 0.04);

⁵Number of stools per day.

^aP = 0.02;

^bP = 0.008;

^cP = 0.040;

^dP = 0.007;

^eP < 0.0001. LS: Laparoscopic surgery; PRT: Prospective randomized trial.