Restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis: A narrative review

Table 1 Meta-analyses comparing the intra-operative, short-term, and functional outcomes of open vs laparoscopic restorative proctocolectomy with ileal pouch-anal anastomosis

Ref.	Number of studies included/N of RCTs	Number of patients	Operative time	Blood loss	Intra-operative mortality	Hospital stay	Post-operative complications	Functional outcomes
Tilney et al[9]	10/1	Open: 178 LS: 175	Higher in LS by 86 minb	Lower in LS by 84 mLb	Not reported	No significant differences	No significant differences	No significant differences1
Ahmed Ali et al[8]	11/1	Open: 354 LS: 253	Higher in LS by 92 minb	Lower in LS by 138 mL	No significant differences	Shorter in LS by 2.12 d	Total Open: 41.5 LS: 37.6 Severe Open: 7.8 LS: 5.1	LS: Shorter time to bowel movement (-1.96 d); no significant difference in daytime and overnight continence, soiling, or urge incontinence
Singh et al[7]	27/1	Open: 1331 LS: 1097	Higher in LS by 70.1 minb	Lower in LS by 89.1 mLb	Not reported	Shorter in LS by 1 d	No significant differences with the exception of wound infection (lower in LS)	LS led to fewer nocturnal bowel movements and reduced pad usage during the day

¹Data based on only 2 studies;

^bP < 0.001. RCT: Randomized controlled trial; LS: Laparoscopic surgery.