Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence?

Table 2 Univariate and multivariate analyses for predictors of overall survival

	Total	5-yr survival (%)	Median survival (mo)	Univariate analysis P	HR	95%CI	Multivariate analysis P
Overall	158	59.7	-	-
Age (≥ 60 yr)	-	-	-	0.133
Gender		-	-	0.097
Male	122	61.5			0.88	0.45-1.74	0.714
Female	36	55.4	-
BMI (≥ 28)				0.080
Yes	37	48.2	46		1.55	0.81-2.98	0.186
No	113	63.6	-
Pre-op AFP (≥ 100 ng/dL)				0.087
Yes	19	51.8	-		1.50	0.68-3.32	0.316
No	129	60.8	-
Cirrhosis	-	-	-	0.950
Alcohol related				0.048
Yes	22	86.4	-		0.30	0.09-1	0.051
No	131	55.5	-
Hepatitis B infection	-	-	-	0.156
Hepatitis C infection	-	-	-	0.130
Others	-	-	-	0.281
Blood type	-	-	-	0.470
Rhesus	-	-	-	0.554
Radiofrequency	-	-	-	0.821
MELD (≥ 15)	-	-	-	0.721
Chemo-embolization	-	-	-	0.877
Tumor alcoholization	-	-	-	0.118
Graft/body % (≥ 2)	-	-	-	0.163
No. of lesions (> 3)	-	-	-	0.819
Largest lesion (≥ 30 mm)	-	-	-	0.640
Edmond-Steiner degree				0.013
III-IV	88	48.9	51		2.19	1.07-4.47	0.031
0-II	59	74.4	-
Vascular invasion	-	-	-	0.290
Microsatellite lesions	-	-	-	0.283
Cholangiocarcinoma	-	-	-	0.957
IBS				0.510
Yes	122	59.5	-		1.56	0.74-3.30	0.237
No	36	64.5	-

BMI: Body mass index; AFP: Alpha-feto protein; IBS: Intraoperative blood salvage; MELD: Model of End-Stage Liver Disease. The number of patients included in multivariate model is 141.