Copyright
©The Author(s) 2015.
World J Gastrointest Surg. Mar 27, 2015; 7(3): 25-32
Published online Mar 27, 2015. doi: 10.4240/wjgs.v7.i3.25
Published online Mar 27, 2015. doi: 10.4240/wjgs.v7.i3.25
Table 2 Clinical features and colon cancer risk in Hamartomatous Polyposis Syndromes, according to literature series
| Syndrome | Main clinical features polyp distribution | Increased risk of other tumors | Colon cancer risk |
| Juvenile Polyposis | Juvenile polyps Distribution: large bowel (mainly), small bowel, stomach | Gastric and colorectal | 39%-68% |
| Peutz-Jeghers | Peutz-Jeghers polyps Typical melanotic oral and dermic pigmentations Distribution: small bowel, large bowel, stomach | Gastric, small bowel, pancreas, colorectal, ovary, uterus, breasts, sex cords | 39%-57% |
| PTEN | Mucocutaneous tumors (multiple trichilemmomas) Distribution: Small bowel, large bowel, stomach | Breast, thyroid, retina and uterus cancer | 18% |
- Citation: Campos FG, Figueiredo MN, Martinez CAR. Colorectal cancer risk in hamartomatous polyposis syndromes. World J Gastrointest Surg 2015; 7(3): 25-32
- URL: https://www.wjgnet.com/1948-9366/full/v7/i3/25.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v7.i3.25