Systemic inflammation and immune response after laparotomy vs laparoscopy in patients with acute cholecystitis, complicated by peritonitis

Figure 2 Severe leukocytosis was observed only after open cholecystectomy, but not after aparoscopic cholecystectomy, mostly due to an increment of neutrophils on day 1 and 3. Regarding Neutrophilis values, the difference between baseline values and post-operative values were significant in both groups (using the Friedman test, ^aP < 0.05). LC: Laparoscopic cholecystectomy; OC: Open cholecystectomy.