Systemic inflammation and immune response after laparotomy vs laparoscopy in patients with acute cholecystitis, complicated by peritonitis

Table 3 The number of blood cultures positive for organism was increased in the open cholecystectomy group as compared with the laparoscopic cholecystectomy group n (%)

Time intervention	Opencholecystectomy(n = 22)	Laparoscopic cholecystectomy(n = 20)	P value
Within 60 min before	10 (45.4)	8 (40)	NS
Within 60 min after1	10 (45.4)	4 (20)	0.001
Within 7 d after	1 (4.5)	0	NS

¹Significant difference between groups, using Fisher’s exact tests, P < 0.05; NS: No significant difference between groups, using χ² o Fisher’s exact tests, P > 0.05.