Perianal Paget’s disease with concomitant rectal cancer: A case report

Figure 3 Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis with volcano and scatter plots of differentially expressed mRNAs between cancer and adjacent tissues. A: Gene Ontology (GO) classification; B: GO enrichment. X-axis label represents rich factor, Y-axis label represents GO term. Size, shape and color of the bubble represent amount of differentially expressed (DE) mRNAs, classification and enrichment significance, respectively; C: Kyoto Encyclopedia of Genes and Genomes (KEGG) classification; D: KEGG enrichment. X-axis label represents rich factor, Y-axis label represents pathway. Size, and color of the bubble represent amount of DE mRNAs and enrichment significance, respectively; E: Up-regulated and down-regulated mRNAs were showed by the volcano plot; F: The differential expression of mRNAs between cancerous and adjacent normal tissues was evaluated using a scatter plot. Red points indicate up-regulated mRNAs, and blue points indicate down-regulated mRNAs. GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; DE: Differentially expressed; T: Tumor; N: Adjacent normal tissue.