Matched analysis of long-term oncological outcomes between watch-and-wait strategy and radical surgery after neoadjuvant therapy for rectal cancer

doi:10.4240/wjgs.121131

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Sep 27, 2026; 18(9): 121131
Published online Sep 27, 2026. doi: 10.4240/wjgs.121131

Table 2 Comparison of recurrence patterns between the watch-and-wait and radical surgery groups, n (%)

Group	Case number	Local regrowth/recurrence	Distant metastasis	Overall recurrence rate
Watch-and-wait group	45	5 (11.11)	1 (2.22)	6 (13.33)
Radical surgery group	45	2 (4.44)	2 (4.44)	4 (8.89)
χ² value	-	-	-	0.480
P value	-	-	-	0.736

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Citation: Li ZJ, Zhang K. Matched analysis of long-term oncological outcomes between watch-and-wait strategy and radical surgery after neoadjuvant therapy for rectal cancer. World J Gastrointest Surg 2026; 18(9): 121131
URL: https://www.wjgnet.com/1948-9366/full/v18/i9/121131.htm
DOI: https://dx.doi.org/10.4240/wjgs.121131