Multi-omics reveal the effects of probiotics on the postoperative rehabilitation of patients with esophageal cancer

Figure 3 Probiotic therapy influenced feces metabolic profiles after operation. A: A volcano plot of the MS1 differentially abundant metabolites under the positive ion mode; B: A volcano plot of the MS1 differentially abundant metabolites under the negative ion mode; C-F: An orthogonal partial least squares discriminant analysis (OPLS-DA) score map and OPLS-DA permutation test in the positive ion mode; the abscissa represents the decomposition degree of the first main component, and the ordinate represents the decomposition degree of the second main component (C and E). An OPLS-DA score map and OPLS-DA permutation test in the negative ion mode; the abscissa represents the decomposition degree of the first main component, and the ordinate represents the decomposition degree of the second main component (D and F). NC group: Control group; PRO group: Probiotic group; FC: Fold change; OPLS-DA: Orthogonal partial least squares discriminant analysis.