Severe postoperative infections following surgery for digestive system diseases

Table 1 Baseline demographic and clinical characteristics of patients, n (%)/mean ± SD

Variable	Infection group (n = 38)	Non-infection group (n = 118)	t/χ2	P value
Age (years)	63.2 ± 11.8	57.2 ± 12.1	2.70	0.008
Male sex	25 (65.8)	67 (56.8)	0.94	0.332
BMI (kg/m2)	24.8 ± 3.9	23.6 ± 3.5	1.78	0.077
Smoking	18 (47.4)	38 (32.2)	2.84	0.092
Diabetes mellitus	17 (44.7)	20 (16.9)	12.06	< 0.001
Hypertension	16 (42.1)	35 (29.7)	1.98	0.160
COPD	5 (13.2)	8 (6.8)	1.48	0.224
Chronic liver disease	8 (21.1)	14 (11.9)	1.98	0.160
Previous abdominal surgery	12 (31.6)	24 (20.3)	2.03	0.154
ASA classification
I-II	18 (47.4)	82 (69.5)	6.08	0.014
III-IV	20 (52.6)	36 (30.5)
NRS 2002 ≥ 3	22 (57.9)	40 (33.9)	6.85	0.009
Albumin (g/L)	32.8 ± 4.6	37.2 ± 4.1	5.62	< 0.001
Hemoglobin (g/L)	112.4 ± 18.6	124.8 ± 16.2	3.94	< 0.001
WBC (× 109/L)	7.8 ± 2.9	6.4 ± 2.1	3.17	0.002
CRP (mg/L, median, IQR)	12.4 (5.8-24.6)	4.2 (1.8-10.5)	3.861	< 0.001
HbA1c (%)	7.2 ± 1.8	5.9 ± 1.1	5.04	< 0.001
Fasting glucose (mmol/L)	7.6 ± 2.4	5.8 ± 1.6	5.20	< 0.001

¹Mann-Whitney U test.

BMI: Body mass index; COPD: Chronic obstructive pulmonary disease; ASA: American Society of Anesthesiologists; NRS: Nutritional Risk Screening; WBC: White blood cell; CRP: C-reactive protein; HbA1c: Glycosylated hemoglobin; IQR: Interquartile range.