Combined inflammation/nutrition-based prognostic score for overall survival in gastric adenocarcinoma: A retrospective cohort study

doi:10.4240/wjgs.121272

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 121272
Published online Aug 27, 2026. doi: 10.4240/wjgs.121272

Table 2 Baseline demographic and clinical characteristics stratified by inflammation/nutrition-based combined score, median (interquartile range)/n (%)

Variable	Total (n = 154)	Low score (0-3, n = 121)	High score (4-6, n = 33)	P value
Age (years)	68 (61-76)	67 (60-74)	75 (70-83)	< 0.001^a
Sex (male)	96 (62.3)	78 (64.5)	18 (54.5)	0.401
Type of surgery				0.050
Subtotal	59 (38.3)	41 (33.9)	18 (54.5)
Total	95 (61.7)	80 (66.1)	15 (45.5)
Neoadjuvant chemotherapy	29 (18.8)	25 (20.7)	4 (12.1)	0.389
Overall mortality	94 (61.0)	65 (53.7)	29 (87.9)	< 0.001^a
TNM stage	n = 151			0.016^a
Stage I	19 (12.6)	18 (14.9)	1 (3.0)
Stage II	45 (29.8)	39 (32.2)	6 (18.2)
Stage III	65 (43.0)	48 (39.7)	17 (51.5)
Stage IV	22 (14.6)	13 (10.7)	9 (27.3)
Perineural invasion	107/153 (69.9)	79 (65.3)	28 (84.8)	0.058
Differentiation (poor)	n = 108			0.136
Poor	48 (44.4)	36 (29.8)	12 (36.4)
Moderate	43 (39.8)	30 (24.8)	13 (39.4)
Good	17 (15.7)	16 (13.2)	1 (3.0)

^aP < 0.05.

Mann Whitney U test was used for age, and χ² was used for the categoric variables. The total number (n) of available cases for variables with missing data is indicated separately. TNM: Tumor-node-metastasis.

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Citation: Çanakcı MH, Kayılıoğlu I, Şimşek A, Dinç T. Combined inflammation/nutrition-based prognostic score for overall survival in gastric adenocarcinoma: A retrospective cohort study. World J Gastrointest Surg 2026; 18(8): 121272
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/121272.htm
DOI: https://dx.doi.org/10.4240/wjgs.121272

Çanakcı MH, Kayılıoğlu I, Şimşek A, Dinç T. Combined inflammation/nutrition-based prognostic score for overall survival in gastric adenocarcinoma: A retrospective cohort study. World J Gastrointest Surg 2026; 18(8): 121272 [DOI: 10.4240/wjgs.121272]

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