Prognostic value of acute liver injury in cirrhotic patients after the transjugular intrahepatic portosystemic shunt procedure

doi:10.4240/wjgs.121016

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World Journal of Gastrointestinal Surgery

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1948-9366

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Surg. Aug 27, 2026; 18(8): 121016
Published online Aug 27, 2026. doi: 10.4240/wjgs.121016

Table 1 Patient characteristics, mean ± SD/n (%)

Variables	All patients (n = 346)	Acute liver injury (n = 74)	No-acute liver injury (n = 272)	P value
Age (year)	54.5 ± 11.3	56.7 ± 12.1	53.9 ± 11.1	0.051
Male gender	246 (71.1)	57 (77.0)	189 (69.5)	0.204
BMI (kg/m²)	22.6 ± 3.0	22.1 ± 2.9	22.7 ± 3.0	0.092
Virus-related cirrhosis	209 (60.4)	42 (56.8)	167 (61.4)	0.469
Ascites	236 (68.2)	25 (33.8)	84 (30.9)	0.648
Hypertension	38 (11.0)	10 (13.5)	28 (10.3)	0.438
Diabetes	58 (16.8)	10 (13.5)	48 (17.6)	0.392
HCC	46 (13.3)	15 (20.3)	31 (11.4)	0.048
Hb (g/L)	81.8 ± 23.6	84.1 ± 21.6	81.2 ± 24.1	0.277
WBC (× 10⁹/L)	4.3 ± 3.1	4.8 ± 4.2	4.1 ± 2.7	0.574
Platelets (× 10⁹/L)	86.7 ± 64.1	89.4 ± 74.4	85.9 ± 61.4	0.552
Albumin (g/L)	33.2 ± 5.4	33.3 ± 5.8	32.7 ± 5.3	0.361
Prealbumin (g/L)	98.4 ± 38.9	106.7 ± 39.5	96.4 ± 38.6	0.082
Globulin (g/L)	28.0 ± 7.0	27.4 ± 5.9	28.2 ± 7.2	0.394
TBIL (µmol/L)	23.6 ± 15.7	21.1 ± 17.5	24.3 ± 14.4	0.008
ALT (U/L)	20.7 ± 8.2	22.2 ± 8.5	20.2 ± 8.0	0.067
AST (U/L)	30.7 ± 12.5	30.6 ± 12.6	30.0 ± 12.5	0.661
Creatinine (µmol/L)	70.9 ± 54.6	87.2 ± 101.6	66.4 ± 30.2	0.002
BUN (mmol/L)	6.7 ± 4.4	7.8 ± 3.8	6.5 ± 4.6	< 0.001
INR	1.3 ± 0.3	1.2 ± 0.2	1.3 ± 0.3	0.084
PT (second)	15.3 ± 2.8	14.7 ± 2.6	15.4 ± 2.8	0.042
Child-Pugh score	7.3 ± 1.5	7.1 ± 1.6	7.4 ± 1.5	0.076
Child-Pugh class
A	87 (25.1)	31 (41.9)	84 (30.9)	0.075
B	200 (57.8)	36 (48.6)	165 (60.7)	0.063
C	59 (17.1)	7 (9.5)	23 (8.5)	0.786
MELD score	9.7 ± 4.1	9.0 ± 4.1	9.9 ± 4.1	0.099
TPMT (mm/m)	11.4 ± 3.4	11.6 ± 3.5	11.4 ± 3.4	0.762
Sarcopenia (yes/no)	103 (46.5)	21 (28.4)	82 (30.1)	0.731

BMI: Body mass index; HCC: Hepatocellular carcinoma; Hb: Hemoglobin; WBC: White blood cell; TBIL: Total bilirubin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; INR: International normalized ratio; PT: Prothrombin time; MELD: Model for End-Stage Liver Disease; TPMT: Transverse psoas muscle thickness.

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Citation: Yin L, Zhang JQ, Zhu YJ, Chu SL, Liu KC, Zhang P, Dong L, Zhang YH, Lu D, Lv WF, Zhou CZ, Cheng DL. Prognostic value of acute liver injury in cirrhotic patients after the transjugular intrahepatic portosystemic shunt procedure. World J Gastrointest Surg 2026; 18(8): 121016
URL: https://www.wjgnet.com/1948-9366/full/v18/i8/121016.htm
DOI: https://dx.doi.org/10.4240/wjgs.121016

Yin L, Zhang JQ, Zhu YJ, Chu SL, Liu KC, Zhang P, Dong L, Zhang YH, Lu D, Lv WF, Zhou CZ, Cheng DL. Prognostic value of acute liver injury in cirrhotic patients after the transjugular intrahepatic portosystemic shunt procedure. World J Gastrointest Surg 2026; 18(8): 121016 [DOI: 10.4240/wjgs.121016]

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